1-(4-Boronophenyl)cyclopropanecarboxylic acid is an organic compound containing a boron group. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C10H9BO2
-Molecular weight: 164.99g/mol
-Melting point: about 130-133°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethyl formamide
Use:
- 1-(4-Boronophenyl)cyclopropanecarboxylic acid is mainly used for C- C bond formation reactions in organic synthesis. It can be used as a catalyst precursor for catalytic asymmetric hydrogenation reactions and asymmetric carbon-carbon bond formation reactions.
-This compound is also commonly used in the fields of pharmaceutical synthesis, materials science and organic optoelectronic devices.
Preparation Method:
The preparation of -1-(4-Boronophenyl)cyclopropanecarboxylic acid usually involves a multi-step reaction. One common method is to first synthesize phenylcyclopropanoyl chloride and then react with a borophenyl Grignard reagent to obtain the desired product.
Safety Information:
-The toxicity and safety data of this compound are limited, so appropriate protective measures should be taken when handling.
-In case of contact with skin, eyes or inhalation of the compound, rinse immediately with plenty of water and seek medical assistance.
-Avoid inhaling dust and skin contact during operation.
-Operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, goggles and protective clothing.
-During use and storage, safe operating procedures and correct laboratory practices should be observed.